CV

Curriculum vitae.

Contact Information

Name Yanjie Chen
Professional Title Research Staff Associate
Email yc4594@columbia.edu
Location Columbia University, 1190 Amsterdam Avenue, New York, NY 10027

Professional Summary

I am a Research Staff Associate in the Dinh Lab at Columbia’s Irving Institute for Cancer Dynamics. My work applies statistics and machine learning to cancer genomics, with a particular focus on clustering algorithms for bulk DNA sequencing data.

Experience

  • 2026 - present

    New York, US

    Research Staff Associate
    Irving Institute for Cancer Dynamics, Columbia University
    Advisor: Khanh N. Dinh.
    • Continued DECODE development
    • Large-scale validation on HPC; DECODE-copy_number_variant & DECODE2
    • Other projects on cancer genomics
  • 2025 - present

    New York, US

    Research Assistant
    Memorial Sloan Kettering Cancer Center
    Advisor: Li-Xuan Qin.
    • Stabilized SyNG-BTS for tumor RNA/miRNA-seq augmentation
    • Large-scale validation and supplementary analysis
  • 2025 - 2025

    New York, US

    Research Intern
    Irving Institute for Cancer Dynamics, Columbia University
    Advisor: Khanh N. Dinh.
    • Developed DECODE to cluster mutations from bulk DNA-seq using population-genetics models
    • Built the analysis pipeline for tumor clonality and subclonal inference

Education

  • 2024 - 2025

    New York, US

    Master
    Columbia University
    Statistics
    • GPA: 3.8/4.0
    • Coursework: Advanced Machine Learning, Deep Learning, Probability Theory, Computational Statistics
  • 2022 - 2024

    Liverpool, UK

    Undergraduate
    University of Liverpool
    Mathematics
    • First Class Honours
    • GPA: 3.9/4.0
    • Coursework: Stochastic Modelling, Statistics and Probability
  • 2020 - 2022

    Suzhou, China

    Undergraduate
    Xi'an Jiaotong-Liverpool University
    Mathematics
    • GPA: 3.7/4.0
    • Coursework: Dynamic Modeling, Linear Algebra, Analysis

Awards

  • 2021
    Undergraduate Academic Excellence Performance Scholarship
    Xi'an Jiaotong-Liverpool University

Skills

Programming: R, Python (PyTorch), Bash/Linux, LaTeX, MATLAB
ML/Stats: Bayesian Inference, Random Forests, Time Series Analysis, NLP, Transformers

Languages

Mandarin : Native
English : Fluent

Interests

Computational Genomics: Bayesian Inference, Causal Inference, Modern ML Solutions

Projects

  • 2026
    Joint Statistical Meetings (JSM) 2026

    Speaker in a topic-contributed paper session, at the invitation of Prof. Marek Kimmel.

    • Talk: “Reliable Inference of Tumor Expansion Rate and Clonality from DNA-Sequencing Data.”
    • Session: “Stochastic Processes Describing Cancer-Related Biological Systems: Modeling and Inference,” Boston, US.
  • 2025
    DitecT Lab, Columbia Engineering

    Data Researcher. Advisor: Xuan Sharon Di.

    • Compiling NYC TLC yellow/green taxi trips with holiday and weather data to evaluate CBD congestion pricing
    • Building a lean cleaning/feature pipeline and performing time-series and causal analyses (DiD, event-study, survival) to quantify demand shifts; exploring substitution and behavioral mechanisms

References

  • Khanh N. Dinh, Ph.D.

    Research Scientist, Irving Institute for Cancer Dynamics, Columbia University. Profile

  • Li-Xuan Qin, Ph.D.

    Attending Biostatistician, Memorial Sloan Kettering Cancer Center. Profile